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Invitrogen
IL-28 (IFN lambda) Monoclonal Antibody (RN28), eBioscience™
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-ELISA-20170216130641.jpg?time=20240507 "IL-28 (IFN lambda) Antibody in ELISA (ELISA)")
-ELISA-20170216130641.jpg?time=20240507)
-ELISA-20170216130641.jpg?time=20240507?time=20240507 "IL-28 (IFN lambda) Antibody (14-7281-81) in ELISA")
Product Details
14-7281-81
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
RN28
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Description: This monoclonal RN28 antibody reacts with IL-28 (IFN lambda), a member of the IFN-lambda family which mediates the induction of anti-viral protection in a wide variety of cells.
Applications Reported: The RN28 antibody has been reported for use in ELISA capture of mouse IL-28.
Applications Tested: This RN28 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of mouse IL-28 in combination with the biotin polyclonal (Product # 13-7282-81) antibody for detection. A suitable range of concentrations of this antibody for ELISA capture is 1.0-4 µg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 4000 pg/mL - 30 pg/mL should be included in each ELISA plate.
Purity: Greater than 90%, as determined by SDS-PAGE.
Aggregation: Less than 10%, as determined by HPLC.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IFN lambda2; IFN-lambda-2; IFN-lambda-3; IFN-lambda2; IL 28; IL 28 A; IL-28A; IL-28B; ILN; interferon alpha; Interferon lambda-2; Interferon lambda-3; Interferon lambda2; interferon-lambda2; Interleukin; interleukin 28; interleukin 28A; interleukin 28B; Interleukin-28A; Interleukin-28B
Gene Aliases: EG330496; IFL-1; Ifnl2; Ifnl3; IL-28A; IL-28B; Il28; Il28a; Il28b; INF-alpha; INF-lambda
UniProt ID: (Mouse) Q4VK74, (Mouse) Q8CGK6
Entrez Gene ID: (Mouse) 330496, (Mouse) 338374
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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