|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||PHA-activated human T-lymphocytes|
|Storage buffer||PBS with 0.2% carrier protein|
|Contains||0.08% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells. To date, a total of 151 CD clusters and subclusters have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
GSK3 inhibition prevents lethal GVHD in mice.
MA1-12259 was used in immunocytochemistry to study the ability of a small molecule GSK3 inhibitor to prevent host-versus-graft disease in a murine humanized xenograft model
|Klamer G,Shen S,Song E,Rice AM,Knight R,Lindeman R,O'Brien TA,Dolnikov A||Experimental hematology (41:39)||2013|