Product References
Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes.
Cancers
Erlichman N,Baram T,Meshel T,Morein D,Da'adoosh B,Ben-Baruch A
500-P28 was used in Enzyme-linked immunosorbent assay to investigate the role of WT-PD-L1 in triple-negative breast cancer.
Fri Feb 18 00:00:00 EST 2022
PLAU directs conversion of fibroblasts to inflammatory cancer-associated fibroblasts, promoting esophageal squamous cell carcinoma progression via uPAR/Akt/NF-κB/IL8 pathway.
Cell death discovery
Fang L,Che Y,Zhang C,Huang J,Lei Y,Lu Z,Sun N,He J
Thu Feb 11 00:00:00 EST 2021
Notch-Mediated Tumor-Stroma-Inflammation Networks Promote Invasive Properties and CXCL8 Expression in Triple-Negative Breast Cancer.
Frontiers in immunology
Liubomirski Y,Lerrer S,Meshel T,Morein D,Rubinstein-Achiasaf L,Sprinzak D,Wiemann S,Körner C,Ehrlich M,Ben-Baruch A
500-P28 was used in Enzyme-linked immunosorbent assay to investigate pro-metastatic chemokines in triple-negative breast cancer.
Thu Oct 01 00:00:00 EDT 2020
Tumor-Stroma-Inflammation Networks Promote Pro-metastatic Chemokines and Aggressiveness Characteristics in Triple-Negative Breast Cancer.
Frontiers in immunology
Liubomirski Y,Lerrer S,Meshel T,Rubinstein-Achiasaf L,Morein D,Wiemann S,Körner C,Ben-Baruch A
500-P28 was used in Enzyme-linked immunosorbent assay to study the impact of tumor-stroma-inflammation networks on pro-metastatic phenotypes in triple-negative breast cancer (TNBC) to identify a novel tumor-stroma-inflammation networks that may promote TNBC aggressiveness by increasing the pro-malignancy potential of the TME and of the tumor cells themselves, and reveal key roles for CXCL8 in mediating these metastasis-promoting activities.
Mon Aug 10 00:00:00 EDT 2020
Co-Inflammatory Roles of TGFβ1 in the Presence of TNFα Drive a Pro-inflammatory Fate in Mesenchymal Stem Cells.
Frontiers in immunology
Lerrer S,Liubomirski Y,Bott A,Abnaof K,Oren N,Yousaf A,Körner C,Meshel T,Wiemann S,Ben-Baruch A
500-P28 was used in Enzyme-linked immunosorbent assay to demonstrate a TNFα + TGFβ1-driven pro-inflammatory fate in MSCs, identify specific molecular mechanisms involved, and propose that TNFα + TGFβ1-stimulated MSCs influence the tumor niche.
Wed Nov 20 00:00:00 EST 2019
The cerebral cavernous malformation 3 gene is necessary for senescence induction.
Aging cell
Guerrero A,Iglesias C,Raguz S,Floridia E,Gil J,Pombo CM,Zalvide J
Wed Apr 01 00:00:00 EDT 2015
The cerebral cavernous malformation 3 gene is necessary for senescence induction.
Aging cell
Guerrero A,Iglesias C,Raguz S,Floridia E,Gil J,Pombo CM,Zalvide J
Wed Apr 01 00:00:00 EDT 2015
The cerebral cavernous malformation 3 gene is necessary for senescence induction.
Aging cell
Guerrero A,Iglesias C,Raguz S,Floridia E,Gil J,Pombo CM,Zalvide J
Wed Apr 01 00:00:00 EDT 2015
Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.
Tissue engineering. Part A
Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ
500-P28 was used in Blocking experiments to demonstrate that accumulation of infused endothelial progenitors can be enriched using biomaterial-based delivery of VEGF and SDF.
Wed Apr 01 00:00:00 EDT 2015
Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-α and the NF-κB pathway.
Stem cell research & therapy
Katanov C,Lerrer S,Liubomirski Y,Leider-Trejo L,Meshel T,Bar J,Feniger-Barish R,Kamer I,Soria-Artzi G,Kahani H,Banerjee D,Ben-Baruch A
500-P28 was used in Enzyme-linked immunosorbent assay to study the impact of tumour necrosis factor α and interleukin 1β on the inflammatory phenotype of cancer-associated fibroblasts and mesenchymal stem cells.
Fri May 01 00:00:00 EDT 2015
Tumor microenvironment B cells increase bladder cancer metastasis via modulation of the IL-8/androgen receptor (AR)/MMPs signals.
Oncotarget
Ou Z,Wang Y,Liu L,Li L,Yeh S,Qi L,Chang C
500-P28 was used in Neutralisation experiments to study the effects of B cells on bladder cancer cell invasion via IL-8/androgen receptor signals, and show that blocking the IL-8/AR/MMPs signals partially reversed the infiltrating B cells capacity to increase the bladder cancer cell invasion.
Tue Sep 22 00:00:00 EDT 2015
The inflammatory cytokine TNFα cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells.
BMC cancer
Leibovich-Rivkin T,Liubomirski Y,Meshel T,Abashidze A,Brisker D,Solomon H,Rotter V,Weil M,Ben-Baruch A
500-P28 was used in Enzyme-linked immunosorbent assay to determine the relative contribution of two processes to breast cancer progression: (1) Intrinsic events, such as activation of the Ras pathway and down-regulation of p53; (2) The inflammatory cytokines TNFα and IL-1β, shown in our published studies to be highly expressed in tumors of >80% of breast cancer patients with recurrent disease.
Thu Mar 06 00:00:00 EST 2014
Progression of luminal breast tumors is promoted by ménage à trois between the inflammatory cytokine TNFα and the hormonal and growth-supporting arms of the tumor microenvironment.
Mediators of inflammation
Weitzenfeld P,Meron N,Leibovich-Rivkin T,Meshel T,Ben-Baruch A
500-P28 was used in Enzyme-linked immunosorbent assay to indicate that TNF α can turn into a strong prometastatic factor, suggesting a paradigm shift in which clinically approved inhibitors of TNFα would be applied in breast cancer therapy.
Thu Jun 05 00:00:00 EDT 2014
Inflammatory factors of the tumor microenvironment induce plasticity in nontransformed breast epithelial cells: EMT, invasion, and collapse of normally organized breast textures.
Neoplasia (New York, N.Y.)
Leibovich-Rivkin T,Liubomirski Y,Bernstein B,Meshel T,Ben-Baruch A
500-P28 was used in Enzyme-linked immunosorbent assay to reveal novel pathways through which the inflammatory microenvironment may contribute to relapsed disease in breast cancer.
Sun Dec 01 00:00:00 EST 2013
Spindle shaped human mesenchymal stem/stromal cells from amniotic fluid promote neovascularization.
PloS one
Roubelakis MG,Tsaknakis G,Pappa KI,Anagnou NP,Watt SM
Fri Sep 06 00:00:00 EDT 2013
Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2.
PloS one
Dwyer J,Hebda JK,Le Guelte A,Galan-Moya EM,Smith SS,Azzi S,Bidere N,Gavard J
500-P28 was used in Western Blotting to investigate the effects of Glioblastoma-produced interleukin-8 on endothelial homeostasis and glioblastoma cell secretions.
Wed Mar 06 00:00:00 EST 2013
Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2.
PloS one
Dwyer J,Hebda JK,Le Guelte A,Galan-Moya EM,Smith SS,Azzi S,Bidere N,Gavard J
500-P28 was used in Western Blotting to investigate the effects of Glioblastoma-produced interleukin-8 on endothelial homeostasis and glioblastoma cell secretions.
Wed Mar 06 00:00:00 EST 2013
Disease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms.
The Journal of biological chemistry
Chiang NY,Hsiao CC,Huang YS,Chen HY,Hsieh IJ,Chang GW,Lin HH
Fri Apr 22 00:00:00 EDT 2011
Predominant expression of CCL2 at the tumor site of prostate cancer patients directs a selective loss of immunological tolerance to CCL2 that could be amplified in a beneficial manner.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Weinberg U,Shaked Y,Alami J,Dumont D,Friedman B,Stein A,Karin N
Fri Jan 15 00:00:00 EST 2010
Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.
Journal of immunology (Baltimore, Md. : 1950)
Rius C,Abu-Taha M,Hermenegildo C,Piqueras L,Cerda-Nicolas JM,Issekutz AC,Estañ L,Cortijo J,Morcillo EJ,Orallo F,Sanz MJ
Wed Sep 15 00:00:00 EDT 2010
Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance.
The Journal of biological chemistry
Lu B,Yadav S,Shah PG,Liu T,Tian B,Pukszta S,Villaluna N,Kutejová E,Newlon CS,Santos JH,Suzuki CK
Fri Jun 15 00:00:00 EDT 2007
Generation and growth of CD28nullCD8+ memory T cells mediated by IL-15 and its induced cytokines.
Journal of immunology (Baltimore, Md. : 1950)
Chiu WK,Fann M,Weng NP
Fri Dec 01 00:00:00 EST 2006
Generation and growth of CD28nullCD8+ memory T cells mediated by IL-15 and its induced cytokines.
Journal of immunology (Baltimore, Md. : 1950)
Chiu WK,Fann M,Weng NP
Fri Dec 01 00:00:00 EST 2006
The role of CXCR2/CXCR2 ligand biological axis in renal cell carcinoma.
Journal of immunology (Baltimore, Md. : 1950)
Mestas J,Burdick MD,Reckamp K,Pantuck A,Figlin RA,Strieter RM
Sat Oct 15 00:00:00 EDT 2005
Characterization of a novel chemokine-containing storage granule in endothelial cells: evidence for preferential exocytosis mediated by protein kinase A and diacylglycerol.
Journal of immunology (Baltimore, Md. : 1950)
Øynebråten I,Barois N,Hagelsteen K,Johansen FE,Bakke O,Haraldsen G
Sat Oct 15 00:00:00 EDT 2005
Cytolytically inactive terminal complement complex causes transendothelial migration of polymorphonuclear leukocytes in vitro and in vivo.
Blood
Dobrina A,Pausa M,Fischetti F,Bulla R,Vecile E,Ferrero E,Mantovani A,Tedesco F
Tue Jan 01 00:00:00 EST 2002
Fibrin regulation of interleukin-8 gene expression in human vascular endothelial cells.
Blood
Qi J,Goralnick S,Kreutzer DL
Sat Nov 01 00:00:00 EST 1997