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IL17RD Antibody (PA5-47288) in Flow
Flow cytometry of IL17RD in HEK293 human cell line transfected with mouse IL-17 RD/SEF. Samples were incubated in IL17RD polyclonal antibody (Product # PA5-47288) or isotype control antibody followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody.
Product Details
PA5-47288
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-17RD/SEF Gly28-Arg299
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606763
Product Specific Information
In direct ELISAs, approximately 40% cross-reactivity with recombinant human IL-17 RD is observed and less than 1% cross-reactivity with recombinant mouse (rm) IL-17 RC and rmIL-17B R is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IL-17 receptor D; IL-17RD; Interleukin-17 receptor D; Interleukin-17 receptor-like protein; mSef; Sef homolog
Gene Aliases: 2810004A10Rik; AI428510; Il17rd; Il17rlm; Sef; Sef-S
UniProt ID: (Mouse) Q8JZL1
Entrez Gene ID: (Mouse) 171463
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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