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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.5-3 µg/mL | - |
Flow Cytometry (Flow) |
2-5 µg/1x10^6 cells | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Non-human primate |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
udSynthetic peptide corresponding to aa 123-136 of human IL-24. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS with 0.2% gelatin |
Contains |
0.05% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2124791 |
Suggested positive control: Jurkat, antigen standard for IL24 (transient overexpression lysate), Jurkat whole cell lysate.
Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IL 24; IL-24; IL-4-induced secreted protein; Interleukin-24; MDA-7; melanocyte-associated Mda-7; Melanoma differentiation-associated gene 7 protein; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein
Gene Aliases: C49A; FISP; IL10B; IL24; MDA7; MOB5; ST16
UniProt ID: (Human) Q13007
Entrez Gene ID: (Human) 11009
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