IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
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Protein Aliases: CD132; CD132 antigen; common cytokine receptor gamma chain; Cytokine receptor common subunit gamma; gammaC; IL 2 receptor subunit gamma; IL 2R subunit gamma; IL 2RG; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL2RG; IMD4; interleukin 2 receptor, gamma; interleukin 2 receptor, gamma (severe combined immunodeficiency); Interleukin-2 receptor subunit gamma; p64; SCIDX; SCIDX1
Gene Aliases: [g]c; Ab2-183; CD132; CIDX; gamma(c); gc; IL-2RG; IL2RG; IMD4; P64; SCIDX; SCIDX1