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Invitrogen
IL2RG Polyclonal Antibody
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FIGURE: 1 / 5
IL2RG Antibody (PA5-26461) in IHC (PFA)
Immunohistochemistry analysis of IL2RG in 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized human spleen tissue. Samples were incubated with IL2RG polyclonal antibody (Product # PA5-26461) using a dilution of 1:25 followed by Alexa Fluor 488-conjugated goat anti-rabbit IgG at a dilution of 1:400 (green). Confocal image showing membrane staining on human spleen tissue. The nuclear counter stain is D... View More
Product Details
PA5-26461
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 76-101 amino acids from the N-terminal region of human IL2RG
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
140 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD132; CD132 antigen; common cytokine receptor gamma chain; Cytokine receptor common subunit gamma; gammaC; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL2R gamma; interleukin 2 receptor, gamma; Interleukin-2 receptor subunit gamma; nonfunctional common cytokine receptor gamma chain; p64; unnamed protein product
Gene Aliases: CD132; CIDX; IL-2RG; IL2RG; IMD4; P64; SCIDX; SCIDX1
UniProt ID: (Human) P31785
Entrez Gene ID: (Human) 3561
mature B cell differentiation
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
immune system process
positive regulation of immunoglobulin production
immune response
signal transduction
gene expression
regulation of gene expression
positive regulation of gene expression
cytokine-mediated signaling pathway
cellular homeostasis
lymphocyte differentiation
B cell differentiation
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
T cell differentiation in thymus
positive regulation of T cell differentiation in thymus
interleukin-15-mediated signaling pathway
interleukin-4-mediated signaling pathway
interleukin-2-mediated signaling pathway
interleukin-7-mediated signaling pathway
interleukin-9-mediated signaling pathway
positive regulation of B cell differentiation
positive regulation of phagocytosis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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