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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ING1 Antibodies

          Invitrogen

          ING1 Polyclonal Antibody

          View all (24) ING1 antibodies

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          Cite ING1 Polyclonal Antibody

          • Antibody Testing Data (4)
          ING1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          ING1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          ING1 Antibody (PA5-47772) in ICC/IF

          Immunocytochemistry analysis of ING1 was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line. The cells were labeled with ING1 Goat Polyclonal Antibody (Product # PA5-47772) using a dilution of 10 µg/mL for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel) counterstained with DAPI (blue, lower panel). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ING1 Antibody in Immunocytochemistry (ICC/IF)
          ING1 Antibody in Immunocytochemistry (ICC/IF)
          ING1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ING1 Antibody in Western Blot (WB)
          ING1 Polyclonal Antibody

          Product Details

          PA5-47772

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          5-15 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          5-15 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          E. coli-derived recombinant human ING1 Met213-Ser327
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS with 5% trehalose

          Contains

          No Preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2576639

          Product Specific Information

          In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) ING2 and less than 1% cross-reactivity with with rhING3, rhING4, and rhING5 is observed.

          Reconstitute at 0.2 mg/mL in sterile PBS.

          Target Information

          This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: growth inhibitor ING1; growth inhibitory protein ING1; inhibitor of growth family, member 1; Inhibitor of growth protein 1; p33ING; tumor suppressor ING1

          View more View less

          Gene Aliases: ING1; p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a

          View more View less

          UniProt ID: (Human) Q9UK53

          View more View less

          Entrez Gene ID: (Human) 3621

          View more View less

          Function(s)
          protein binding zinc ion binding methylated histone binding chromatin/chromatin-binding, or -regulatory protein
          Process(es)
          cell cycle negative regulation of cell proliferation regulation of cell death chromatin modification negative regulation of cell growth
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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