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Product Details
27240-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
INPP5F fusion protein Ag25687
Conjugate
Form
Liquid
Concentration
0.9 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: VKQTKSNVNI GNLRKLGNFT KPEMKVNFLK PNLKVNLWKS DSSLETMENT GVMDKVQAES DGDMSSDNDS YHSDEFLTNS KSDEDRQLAN SLESVGPIDY VLPSCGIIAS APRLGSRSQS LSSTDSSVHA PSEITVAHGS GLGKGQESPL KKSPSAGDVH ILTGFAKPMD IYCHRFVQDA QNKVTHLSET RSVSQQASQE RNQMTNQVSD ETQSESTEQT PSRPSQLDVS LSATGPQFLS VEPAHSVASQ KTPTSASSML ELETGLHVTP SPSESSSSRA VSPFAKIRSS MVQVASITQA GLTHGINFAV SKVQKSPPEP EIINQVQQNE LKKMFIQCQT RIIQI
Target Information
SAC2 is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.1.3.36; hSAC2; Inositol polyphosphate 5-phosphatase F; OCRL 1; Phosphatidylinositide phosphatase SAC2; Sac domain-containing inositol phosphatase 2; Sac domain-containing phosphoinositide 4-phosphatase 2; sac domain-containing phosphoinositide 5-phosphatase 2
Gene Aliases: hSAC2; INPP5F; KIAA0966; MSTP007; MSTP047; MSTPO47; SAC2
UniProt ID: (Human) Q9Y2H2
Entrez Gene ID: (Human) 22876
protein binding
inositol monophosphate 1-phosphatase activity
phosphatidylinositol phosphate 5-phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
protein homodimerization activity
inositol monophosphate 3-phosphatase activity
inositol monophosphate 4-phosphatase activity
phosphatase
positive regulation of receptor recycling
phosphatidylinositol biosynthetic process
cardiac muscle hypertrophy in response to stress
phosphatidylinositol catabolic process
negative regulation of tyrosine phosphorylation of Stat3 protein
phosphatidylinositol dephosphorylation
phosphatidylinositol-mediated signaling
negative regulation of axon regeneration
regulation of protein kinase B signaling
clathrin-mediated endocytosis
regulation of cell motility
regulation of endocytic recycling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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