Peptide sequence: WTDNGPVIPV VYDFGDAQKT ASYYSPYGQR EFTAGFVQFR VFNNERAANA
Sequence homology: Cow: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%
ITLN1 has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes.ITLN1 increases AKT phosphorylation in the absence and presence of insulin. ITLN1 may play a role in the defense system against microorganisms. ITLN1 may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. ITLN1 may be involved in iron metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: calcium-dependent galactosyl-specific lectin; Endothelial lectin HL-1; FLJ20022; Galactofuranose-binding lectin; hIntL; HL1; Intelectin 1 (galactofuranose binding); intelectin 1 (galactofuranose binding)-like; intelectin 2; intelectin 5; intelectin a; Intelectin-1; Intelectin-1a; Intestinal lactoferrin receptor; INTL; ITLN; ITLN-1; LFR; Omentin
Gene Aliases: hIntL; HL-1; HL1; INTL; ITLN; ITLN1; Itln1a; Itln2; Itln5; Itlna; LFR; omentin; UNQ640/PRO1270