Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 2
Recommended positive controls: 293T, H1299, HeLaS3, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (91%), Rat (92%), Xenopus laevis (80%), Chicken (81%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: inosine triphosphatase (nucleoside triphosphate pyrophosphatase); Inosine triphosphate pyrophosphatase; inosine triphosphate pyrophosphohydrolase; ITPase; My049 protein; Non-canonical purine NTP pyrophosphatase; Non-standard purine NTP pyrophosphatase; NTPase; Nucleoside-triphosphate diphosphatase; Nucleoside-triphosphate pyrophosphatase; Putative oncogene protein hlc14-06-p
Gene Aliases: C20orf37; dJ794I6.3; HLC14-06-P; ITPA; ITPase; My049; NTPase; OK/SW-cl.9
UniProt ID: (Human) Q9BY32
Entrez Gene ID: (Human) 3704
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