Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-53702
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ITSN1. Recombinant protein control fragment (Product #RP-91801).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642830
Product Specific Information
Immunogen sequence: ITVLEQQDMW WFGEVQGQKG WFPKSYVKLI SGPIRKSTSM DSGSSESPAS LKRVASPAAK PVVSGEEFIA MYTYESSEQG DLTFQQGDVI LVTKKDGDWW
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 87%.
Target Information
The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: human intersectin-SH3 domain-containing protein SH3P17; intersectin 1 (SH3 domain protein); intersectin 1 short form variant 3; intersectin 1 short form variant, 11; intersectin short variant 12; Intersectin-1; MGC134948; MGC134949; SH3 domain-containing protein 1A; SH3P17; Src homology 3 domain-containing protein
Gene Aliases: ITSN; ITSN1; SH3D1A; SH3P17
UniProt ID: (Human) Q15811
Entrez Gene ID: (Human) 6453
small GTPase mediated signal transduction
regulation of Rho protein signal transduction
positive regulation of phosphorylation
positive regulation of apoptotic process
negative regulation of neuron apoptotic process
positive regulation of GTPase activity
ephrin receptor signaling pathway
synaptic vesicle endocytosis
regulation of small GTPase mediated signal transduction
positive regulation of protein kinase B signaling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support