Product References
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Frontiers in pharmacology
Mao J,Yi M,Wang R,Huang Y,Chen M
Sat Apr 09 00:00:00 EDT 2022
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Frontiers in pharmacology
Yao H,Sun Y,Song S,Qi Y,Tao X,Xu L,Yin L,Han X,Xu Y,Li H,Sun H,Peng J
Wed Sep 30 00:00:00 EDT 2020
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H2S System.
Frontiers in pharmacology
Peng J,Tang ZH,Ren Z,He B,Zeng Y,Liu LS,Wang Z,Wei DH,Zheng XL,Jiang ZS
Wed Sep 30 00:00:00 EDT 2020
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Frontiers in pharmacology
Liang S,Lv ZT,Zhang JM,Wang YT,Dong YH,Wang ZG,Chen K,Cheng P,Yang Q,Guo FJ,Lu WW,Zhu WT,Chen AM
Tue Sep 29 00:00:00 EDT 2020
Knockdown of cathepsin D protects dopaminergic neurons against neuroinflammation-mediated neurotoxicity through inhibition of NF-κB signalling pathway in Parkinson's disease model.
Clinical and experimental pharmacology & physiology
Gan P,Xia Q,Hang G,Zhou Y,Qian X,Wang X,Ding L
Mon Apr 01 00:00:00 EDT 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 EST 2019
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Brain, behavior, and immunity
Xu B,Zang SC,Li SZ,Guo JR,Wang JF,Wang D,Zhang LP,Yang HM,Lian S
Fri Feb 01 00:00:00 EST 2019
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
International immunopharmacology
Wang D,Lao L,Pang X,Qiao Q,Pang L,Feng Z,Bai F,Sun X,Lin X,Wei J
Sat Dec 01 00:00:00 EST 2018
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Fan L,Xiao Q,Zhang L,Wang X,Huang Q,Li S,Zhao X,Li Z
Sat Dec 01 00:00:00 EST 2018
Protective effects of dioscin against systemic inflammatory response syndromevia adjusting TLR2/MyD88/NF‑κb signal pathway.
International immunopharmacology
Zhao X,Yin L,Fang L,Xu L,Sun P,Xu M,Liu K,Peng J
Sat Dec 01 00:00:00 EST 2018
RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β.
Genes & development
Rubio RM,Depledge DP,Bianco C,Thompson L,Mohr I
Sat Dec 01 00:00:00 EST 2018
ACT001 can prevent and reverse tamoxifen resistance in human breast cancer cell lines by inhibiting NF-κB activation.
Journal of cellular biochemistry
Jin XH,Jia YS,Shi YH,Li QY,Bao SQ,Lu WP,Tong ZS
Sun Nov 18 00:00:00 EST 2018
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
Biochemical and biophysical research communications
Zhang LM,Zhang J,Zhang Y,Wang L,Fei C,Yi ZW,Dong L
Fri Nov 02 00:00:00 EDT 2018
TLR4 signaling pathway mediates the LPS/ischemia-induced expression of monocytechemotactic protein-induced protein 1 in microglia.
Neuroscience letters
Chen S,Lyu C,Zhou J,Huang S,Zhang Y,Liu G,Liu K,Chen D,Hu Y,Zhou L,Gu Y
Thu Nov 01 00:00:00 EDT 2018
α7nAChR-mediated recruitment of PP1γ promotes TRAF6/NF-κB cascade to facilitate the progression of Hepatocellular Carcinoma.
Molecular carcinogenesis
Wan C,Wu M,Zhang S,Chen Y,Lu C
Thu Nov 01 00:00:00 EDT 2018
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Drug design, development and therapy
Feng J,Chen K,Xia Y,Wu L,Li J,Li S,Wang W,Lu X,Liu T,Guo C
Wed Oct 31 00:00:00 EDT 2018
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Medical science monitor : international medical journal of experimental and clinical research
Wang C,Luo H,Xu Y,Tao L,Chang C,Shen X
Fri Oct 26 00:00:00 EDT 2018
Lambertellin from Pycnoporus sanguineus MUCL 51321 and its anti-inflammatory effect via modulation of MAPK and NF-κB signaling pathways.
Bioorganic chemistry
Jouda JB,Mfotie Njoya E,Mbazoa CD,Zhou Z,Meli Lannang A,Wandji J,Shiono Y,Wang F
Mon Oct 01 00:00:00 EDT 2018
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Shen D,Tian L,Shen T,Sun H,Liu P
Fri Aug 17 00:00:00 EDT 2018
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
The international journal of biochemistry & cell biology
Ke M,Dong J,Wang Y,Zhang J,Zhang M,Wu Z,Lv Y,Wu R
Wed Aug 01 00:00:00 EDT 2018
Correlation between the expression of IL‑18 and deep venous thrombosis.
International journal of molecular medicine
Li G,Zhou R,Zhao X,Liu R,Ye C
Wed Aug 01 00:00:00 EDT 2018
Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Lu X,Wei T,Dong Y,Cai Z,Tang L,Liu M
Thu Jul 12 00:00:00 EDT 2018
Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging.
Experimental gerontology
Wang W,Cai G,Chen X
Sun Jul 01 00:00:00 EDT 2018
Protective effect and mechanism of Lactobacillus on cerebral ischemia reperfusion injury in rats.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Wanchao S,Chen M,Zhiguo S,Futang X,Mengmeng S
Fri Jun 15 00:00:00 EDT 2018
Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis.
Cell death & disease
Guo Y,Min Z,Jiang C,Wang W,Yan J,Xu P,Xu K,Xu J,Sun M,Zhao Y,Hussain S,Zhang R,Wang Q,Han Y,Zhang F,Zhu W,Li D,Meng L,Sun J,Lu S
Wed Jun 13 00:00:00 EDT 2018
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
Molecular therapy. Nucleic acids
Cen B,Liao W,Wang Z,Gao L,Wei Y,Huang W,He S,Wang W,Liu X,Pan X,Ji A
Fri Jun 01 00:00:00 EDT 2018
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
Molecular therapy. Nucleic acids
Cen B,Liao W,Wang Z,Gao L,Wei Y,Huang W,He S,Wang W,Liu X,Pan X,Ji A
Fri Jun 01 00:00:00 EDT 2018
LPS‑induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF‑κB, STAT3 or AP‑1 activation.
Molecular medicine reports
Liu X,Yin S,Chen Y,Wu Y,Zheng W,Dong H,Bai Y,Qin Y,Li J,Feng S,Zhao P
Sun Apr 01 00:00:00 EDT 2018
Lipoxin A4 may attenuate the progression of obesity-related glomerulopathy by inhibiting NF-κB and ERK/p38 MAPK-dependent inflammation.
Life sciences
Guo YP,Jiang HK,Jiang H,Tian HY,Li L
Sun Apr 01 00:00:00 EDT 2018
Scandoside Exerts Anti-Inflammatory Effect Via Suppressing NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Li J,Liu H,Yang Z,Zhou F,Wei T,Dong Y,Xue H,Tang L,Liu M
Sat Feb 03 00:00:00 EST 2018
The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway.
Journal of cellular biochemistry
Ji Y,Cao L,Zeng L,Zhang Z,Xiao Q,Guan P,Chen S,Chen Y,Wang M,Guo D
Thu Feb 01 00:00:00 EST 2018
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Oncotarget
Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z
Fri Dec 29 00:00:00 EST 2017
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Oncotarget
Lian S,Guo J,Wang L,Li W,Wang J,Ji H,Kong F,Xu B,Li S,Yang H
Fri Dec 29 00:00:00 EST 2017
Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20.
Inflammation
Zhao H,Xia Y,Gan H
Fri Dec 01 00:00:00 EST 2017
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
The EMBO journal
Khan MR,Xiang S,Song Z,Wu M
Fri Dec 01 00:00:00 EST 2017
Calcitonin gene-related peptide exerts anti-inflammatory property through regulating murine macrophages polarization in vitro.
Molecular immunology
Duan JX,Zhou Y,Zhou AY,Guan XX,Liu T,Yang HH,Xie H,Chen P
Wed Nov 01 00:00:00 EDT 2017
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
European journal of pharmacology
Chen HB,Luo CD,Liang JL,Zhang ZB,Lin GS,Wu JZ,Li CL,Tan LH,Yang XB,Su ZR,Xie JH,Zeng HF
Fri Sep 15 00:00:00 EDT 2017
Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage.
Journal of virology
Qian S,Fan W,Liu T,Wu M,Zhang H,Cui X,Zhou Y,Hu J,Wei S,Chen H,Li X,Qian P
Tue Aug 15 00:00:00 EDT 2017
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Molecular medicine reports
Liu CC,Zhang Y,Dai BL,Ma YJ,Zhang Q,Wang Y,Yang H
Tue Aug 01 00:00:00 EDT 2017
ApoE Influences the Blood-Brain Barrier Through the NF-κB/MMP-9 Pathway After Traumatic Brain Injury.
Scientific reports
Teng Z,Guo Z,Zhong J,Cheng C,Huang Z,Wu Y,Tang S,Luo C,Peng X,Wu H,Sun X,Jiang L
Thu Jul 27 00:00:00 EDT 2017
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
International immunopharmacology
Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B
Mon May 01 00:00:00 EDT 2017
Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1G93A ALS Mice.
Neurochemical research
Wang W,Duan W,Wang Y,Wen D,Liu Y,Li Z,Hu H,Cui H,Cui C,Lin H,Li C
Sat Apr 01 00:00:00 EDT 2017
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Food & function
Ren D,Lin D,Alim A,Zheng Q,Yang X
Wed Mar 22 00:00:00 EDT 2017
An excessive increase in glutamate contributes to glucose-toxicity in β-cells via activation of pancreatic NMDA receptors in rodent diabetes.
Scientific reports
Huang XT,Li C,Peng XP,Guo J,Yue SJ,Liu W,Zhao FY,Han JZ,Huang YH,Cheng QM,Zhou ZG,Chen C,Feng DD,Luo ZQ
Fri Mar 17 00:00:00 EDT 2017
Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.
The EMBO journal
Dalet A,Argüello RJ,Combes A,Spinelli L,Jaeger S,Fallet M,Vu Manh TP,Mendes A,Perego J,Reverendo M,Camosseto V,Dalod M,Weil T,Santos MA,Gatti E,Pierre P
Wed Mar 15 00:00:00 EDT 2017
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
Genes & cancer
Yang W,Yang S,Zhang M,Gao D,He T,Guo M
Wed Mar 01 00:00:00 EST 2017
Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-κB Signaling Pathway.
BioMed research international
Liu J,Chen Q,Jian Z,Xiong X,Shao L,Jin T,Zhu X,Wang L
Thu Feb 09 00:00:00 EST 2017
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
Molecular immunology
Fan W,Liu T,Li X,Zhou Y,Wu M,Cui X,Chen H,Qian P
Wed Feb 01 00:00:00 EST 2017
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Biochemical and biophysical research communications
Tang J,Dong Q
Sun Jan 22 00:00:00 EST 2017
Dihydroartemisinin protects against alcoholic liver injury through alleviating hepatocyte steatosis in a farnesoid X receptor-dependent manner.
Toxicology and applied pharmacology
Xu W,Lu C,Yao L,Zhang F,Shao J,Zheng S
Sun Jan 15 00:00:00 EST 2017
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
Investigative ophthalmology & visual science
Gu R,Lei B,Jiang C,Xu G
Sun Jan 01 00:00:00 EST 2017
Etomidate inhibits nuclear factor-κB through decreased expression of glucocorticoid receptor in septic rats.
Molecular medicine reports
Zhang Y,Li RM,Wang C,Liu N,Lv S,Xiong JY
Thu Dec 01 00:00:00 EST 2016
An injectable silk sericin hydrogel promotes cardiac functional recovery after ischemic myocardial infarction.
Acta biomaterialia
Song Y,Zhang C,Zhang J,Sun N,Huang K,Li H,Wang Z,Huang K,Wang L
Thu Sep 01 00:00:00 EDT 2016
Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling.
Acta pharmacologica Sinica
Zhou ZY,Ren LW,Zhan P,Yang HY,Chai DD,Yu ZW
Mon Aug 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65.
Scientific reports
Liu Q,Zhang Z,Zheng Z,Zheng C,Liu Y,Hu Q,Ke X,Wang H
Wed Jun 22 00:00:00 EDT 2016
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
Scientific reports
He M,Wang M,Huang Y,Peng W,Zheng Z,Xia N,Xu J,Tian D
Wed Jun 08 00:00:00 EDT 2016
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Autophagy
Huang Q,Zhan L,Cao H,Li J,Lyu Y,Guo X,Zhang J,Ji L,Ren T,An J,Liu B,Nie Y,Xing J
Thu Jun 02 00:00:00 EDT 2016
Inhibitory effects of S-allylmercaptocysteine against benzo(a)pyrene-induced precancerous carcinogenesis in human lung cells.
International immunopharmacology
Wang K,Wang Y,Qi Q,Zhang F,Zhang Y,Zhu X,Liu G,Luan Y,Zhao Z,Cai J,Cao J,Li S
Sun May 01 00:00:00 EDT 2016
Matrine displayed antiviral activity in porcine alveolar macrophages co-infected by porcine reproductive and respiratory syndrome virus and porcine circovirus type 2.
Scientific reports
Sun N,Sun P,Lv H,Sun Y,Guo J,Wang Z,Luo T,Wang S,Li H
Fri Apr 15 00:00:00 EDT 2016
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Chemico-biological interactions
Wu J,Yang C,Guo C,Li X,Yang N,Zhao L,Hang H,Liu S,Chu P,Sun Z,Sun B,Lin Y,Peng J,Han G,Wang S,Tang Z
Mon Jan 25 00:00:00 EST 2016
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Journal of molecular medicine (Berlin, Germany)
Zhai Y,Wu B,Li J,Yao XY,Zhu P,Chen ZN
Fri Jan 01 00:00:00 EST 2016
Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice.
International immunopharmacology
Zhang F,Zhang Y,Wang K,Zhu X,Lin G,Zhao Z,Li S,Cai J,Cao J
Tue Dec 01 00:00:00 EST 2015
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
International journal of molecular sciences
Mao Y,Zhang S,Yu F,Li H,Guo C,Fan X
Thu Sep 10 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Molecular cancer
Wang F,Yang JL,Yu KK,Xu M,Xu YZ,Chen L,Lu YM,Fang HS,Wang XY,Hu ZQ,Li FF,Kan L,Luo J,Wang SY
Tue Jan 27 00:00:00 EST 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo.
International journal of molecular medicine
Shi X,Chen G,Liu X,Qiu Y,Yang S,Zhang Y,Fang X,Zhang C,Liu X
Thu Jan 01 00:00:00 EST 2015
Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation.
Journal of virology
Wang K,Ni L,Wang S,Zheng C
Tue Jul 01 00:00:00 EDT 2014
Chlorogenic acid prevents isoproterenol-induced hypertrophy in neonatal rat myocytes.
Toxicology letters
Li Y,Shen D,Tang X,Li X,Wo D,Yan H,Song R,Feng J,Li P,Zhang J,Li J
Fri May 02 00:00:00 EDT 2014
14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.
PloS one
Tang S,Bao H,Zhang Y,Yao J,Yang P,Chen X
Tue Dec 03 00:00:00 EST 2013
MG132-mediated inhibition of the ubiquitin-proteasome pathway ameliorates cancer cachexia.
Journal of cancer research and clinical oncology
Zhang L,Tang H,Kou Y,Li R,Zheng Y,Wang Q,Zhou X,Jin L
Mon Jul 01 00:00:00 EDT 2013
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
International journal of oncology
Luo J,Zhou H,Wang F,Xia X,Sun Q,Wang R,Cheng B
Wed May 01 00:00:00 EDT 2013