|Tested species reactivity||Human, Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Guinea pig / IgG|
|Immunogen||Full length human protein.|
|Storage buffer||whole serum diluted in PBS, pH 7.2, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||1:50 - 1:100|
|Immunohistochemistry (Frozen) (IHC (F))||1:50-1:100|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 2 publications below|
PA1-26938 detects Insulin from human and mouse samples.
PA1-26938 has been successfully used in, immunocytochemistry, immunohistochemistry (frozen), and immunohistochemistry (paraffin) procedures.
The PA1-26938 immunogen is full length human protein.
Insulin is a hormone that is synthesized, stored and secreted by beta islets of Langerhans cells of the pancreas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Characterization of age-associated alterations of islet function and structure in diabetic mutant cryptochrome 1 transgenic mice.
PA1-26938 was used in immunohistochemistry to study temporal changes in pancreatic islet biology in transgenic mice expressing a mutant form of cryptochrome-1 associated with the development of diabetes
|Okano S,Hayasaka K,Igarashi M,Togashi Y,Nakajima O||Journal of diabetes investigation (4:428)||2013|
Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice.
PA1-26938 was used in immunohistochemistry to investigate the role of sphingomyelin synthase 1 in mitochondrial function and the intracellular balance of reactive oxygen species
|Yano M,Watanabe K,Yamamoto T,Ikeda K,Senokuchi T,Lu M,Kadomatsu T,Tsukano H,Ikawa M,Okabe M,Yamaoka S,Okazaki T,Umehara H,Gotoh T,Song WJ,Node K,Taguchi R,Yamagata K,Oike Y||The Journal of biological chemistry (286:3992)||2011|