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|Tested species reactivity||Mouse|
|Host / Isotype||Rat / IgG1, kappa|
|Immunogen||Mouse CD41 protein.|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
alpha IIb; alpha subunit; BDPLT2; CD41; CD41B; GP IIb; GP2B; GPalpha IIb; GPIIb; GTA; HPA3; integrin alpha-IIb; ITGA2B; platelet fibrinogen receptor; platelet glycoprotein IIb of IIb/II Ia complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK
AI172977; alphaIIb; CD41; CD41B; GpIIb; Itga2b