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Proteintech
Integrin beta-6 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
21703-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Integrin beta-6 Fusion Protein Ag16319 (139-434 aa encoded by BC121178)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDLSASMDD DLNTIKELGS RLSKEMSKLT SNFRLGFGSF VEKPVSPFVK TTPEEIANPC SSIPYFCLPT FGFKHILPLT NDAERFNEIV KNQKISANID TPEGGFDAIM QAAVCKEKIG WRNDSLHLLV FVSDADSHFG MDSKLAGIVI PNDGLCHLDS KNEYSMSTVL EYPTIGQLID KLVQNNVLLI FAVTQEQVHL YENYAKLIPG ATVGLLQKDS GNILQLIISA YEELRSEVEL EVLGDTEGLN LSFTAICNNG TLFQHQKKCS HMKVGDTASF SVTVNIPHCE RRSRHII (139-434 aa encoded by BC121178 )
Target Information
ITGB6 (Integrin alpha-V/beta-6) is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalization of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-6; integral membrane protein; integrin beta 6; integrin, beta 6; unnamed protein product
Gene Aliases: 2210409C20Rik; 4831415H04Rik; AI1H
UniProt ID: (Human) P18564, (Rat) Q6AYF4, (Mouse) Q9Z0T9
Entrez Gene ID: (Human) 3694, (Rat) 311061, (Mouse) 16420
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
cell migration
cell adhesion mediated by integrin
transforming growth factor beta production
amelogenesis
cell-cell adhesion
cell morphogenesis
inflammatory response
immune response
transforming growth factor beta receptor signaling pathway
biological_process
response to wounding
response to virus
gene expression
wound healing
surfactant homeostasis
skin development
positive regulation of cell adhesion
lung alveolus development
phospholipid homeostasis
hard palate development
bone development
bronchiole development
Langerhans cell differentiation
enamel mineralization
response to growth factor
cellular response to ionizing radiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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