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FIGURE: 1 / 1
JDP2 Antibody (PA5-120335) in WB
Western blot analysis of JDP2 in extracts of various cell lines. Samples were incubated with JDP2 Polyclonal antibody (Product # PA5-120335) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-120335
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human JDP2 (NP_001128521.1).
Conjugate
Unconjugated
Form
Liquid
Concentration
1.54 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2913907
Product Specific Information
Positive test controls include: HeLa, Jurkat, HepG2, Rat testis. The target is usually found in the following locations: Nucleus.
Immunogen sequence: MVAGWPATPP AMMPGQIPDP SVTTGSLPGL GPLTGLPSSA LTVEELKYAD IRNLGAMIAP LHFLEVKLGK RPQPVKSELD EEEERRKRRR EKNKVAAARC RNKKKERTEF LQRESERLEL MNAELKTQIE ELKQERQQLI LMLNRHRPTC IVRTDSVKTP ESEGNPLLEQ LEKK
Target Information
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Jun dimerization protein 2; progesterone receptor co-activator
Gene Aliases: Jdp-2; JDP2; JUNDM2; Jundp2
UniProt ID: (Human) Q8WYK2, (Rat) Q78E65
Entrez Gene ID: (Human) 122953, (Rat) 116674
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
protein binding
protein heterodimerization activity
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
basic leucine zipper transcription factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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