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Proteintech
JNK2 Polyclonal Antibody
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Product Details
51153-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Rabbit
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
JNK2 Fusion Protein Ag1442 (1-424 aa encoded by BC032539)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSDSKCDSQ FYSVQVADST FTVLKRYQQL KPIGSGAQGI VCAAFDTVLG INVAVKKLSR PFQNQTHAKR AYRELVLLKC VNHKNIISLL NVFTPQKTLE EFQDVYLVME LMDANLCQVI HMELDHERMS YLLYQMLCGI KHLHSAGIIH RDLKPSNIVV KSDCTLKILD FGLARTACTN FMMTPYVVTR YYRAPEVILG MGYKENVDIW SVGCIMGELV KGCVIFQGTD HIDQWNKVIE QLGTPSAEFM KKLQPTVRNY VENRPKYPGI KFEELFPDWI FPSESERDKI KTSQARDLLS KMLVIDPDKR ISVDEALRHP YITVWYDPAE AEAPPPQIYD AQLEEREHAI EEWKELIYKE VMDWEERSKN GVVKDQPSDA AVSSNATPSQ SSSINDISSM STEQTLASDT DSSLDASTGP LEGCR (1-424 aa encoded by BC032539)
Target Information
MAPK9 (JNK2) is a serine/threonine kinase which plays an important role in the MAPK pathway. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: c-Jun kinase 2; c-Jun N-terminal kinase 2; JNK; JNK-46; JNK-55; JNK/SAPK alpha; JNK1; JNK1A2; JNK21B1/2; Jun kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAPK 10; MAPK 9; MAPK10; MAPK8; mitogen activated protein kinase 9; Mitogen-activated protein kinase 9; OTTHUMP00000161542; OTTHUMP00000161543; p54-alpha; PRKM8; protein kinase, mitogen-activated 9; SAPK-alpha; SAPK1; SAPK1a; SAPK1c; stress activated protein kinase alpha II; Stress-activated protein kinase 1a; Stress-activated protein kinase JNK2
Gene Aliases: AI851083; JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; MAPK9; p54a; p54aSAPK; PRKM9; SAPK; SAPK1A
UniProt ID: (Human) Q15711, (Rat) P49186, (Mouse) Q9WTU6
Entrez Gene ID: (Human) 5601, (Rat) 50658, (Mouse) 26420
JUN kinase activity
protein binding
ATP binding
transcription factor binding
cysteine-type endopeptidase activator activity involved in apoptotic process
mitogen-activated protein kinase kinase kinase binding
MAP kinase activity
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
release of cytochrome c from mitochondria
positive regulation of protein phosphorylation
protein phosphorylation
protein targeting to mitochondrion
activation of cysteine-type endopeptidase activity involved in apoptotic process
response to stress
JNK cascade
JUN phosphorylation
central nervous system development
response to mechanical stimulus
response to toxic substance
positive regulation of gene expression
positive regulation of macrophage derived foam cell differentiation
positive regulation of cell morphogenesis involved in differentiation
response to amine
neuron projection development
positive regulation of prostaglandin biosynthetic process
regulation of protein ubiquitination
positive regulation of prostaglandin secretion
positive regulation of chemokine production
cellular response to UV
Fc-epsilon receptor signaling pathway
response to drug
regulation of circadian rhythm
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription, DNA-templated
regulation of JNK cascade
response to cadmium ion
rhythmic process
regulation of sequence-specific DNA binding transcription factor activity
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
positive regulation of podosome assembly
positive regulation of apoptotic signaling pathway
MAPK cascade
response to organic substance
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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