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Bethyl Laboratories
JPO2/RAM2 Polyclonal Antibody
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FIGURE: 1 / 1
JPO2/RAM2 Antibody (A300-846A) in WB
Detection of human JPO2/RAM2 by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) and HEK293T (T; 50 µg) cells. Antibodies: Affinity purified rabbit anti-JPO2/RAM2 antibody BL3661 (Product # A300-846A) used for WB at 0.04 µg/mL (A) and 1 µg/mL (B) and used for IP at 3 µg/mg lysate (B). Detection: Chemiluminescence with exposure times of 30 seconds (A and B).
Product Details
A300-846A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 400 and the C-terminus (residue 454) of human c-Myc interacting protein JPO2 (transcription factor RAM2).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Cell division cycle-associated 7-like protein (or RAM2) is a transcription factor which plays a role in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell division cycle associated 7-like; Cell division cycle-associated 7-like protein; Protein JPO2; Transcription factor RAM2
Gene Aliases: CDCA7L; HR1; JPO2; R1; RAM2
UniProt ID: (Human) Q96GN5
Entrez Gene ID: (Human) 55536
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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