FIGURE: 1 / 4
This antibody is predicted to react with Dog, Bovine and Pig.
JunD is a transcription factor which is coded by JunD gene. JunD transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family of protein kinase. Jun proteins are capable of forming dimers with Fos, ATF and CREB family transcription factors to form the AP-1 complex that differentially regulates a variety of target genes involved in cellular growth, proliferation, differentiation and apoptosis. Also, JunD plays an important role in metabolism via modulation of IGF-1 signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: activator protein 1; JUN D; jun D proto-oncogene; JunD-FL isoform; Oncogene Jun-D; Transcription factor AP-1 subunit JunD; Transcription factor JunD
Gene Aliases: AP-1; JUND
UniProt ID: (Human) P17535
Entrez Gene ID: (Human) 3727
Molecular Function: basic leucine zipper transcription factor