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Rockland
KANK2 Polyclonal Antibody
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Product Details
600-401-CD3
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-KANK2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the C-terminus of human KANK2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ankyrin repeat domain 25; Ankyrin repeat domain-containing protein 25; kidney ankyrin repeat-containing protein 2; KN motif and ankyrin repeat domain-containing protein 2; Matrix-remodeling-associated protein 3; SIP; SRC-1-interacting protein; SRC-interacting protein; SRC1-interacting protein
Gene Aliases: AI504612; ANKRD25; BC010245; KANK2; KIAA1518; MXRA3; PPKWH; RGD1563532; SIP
UniProt ID: (Human) Q63ZY3, (Rat) D3ZD05, (Mouse) Q8BX02
Entrez Gene ID: (Human) 25959, (Rat) 100361376, (Mouse) 235041
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
apoptotic process
negative regulation of cell proliferation
negative regulation of intracellular estrogen receptor signaling pathway
negative regulation of programmed cell death
negative regulation of vitamin D receptor signaling pathway
negative regulation of G1/S transition of mitotic cell cycle
regulation of transcription, DNA-templated
negative regulation of stress fiber assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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