PA5-31497 targets KATNA1 in WB applications and shows reactivity with Human samples.
The PA5-31497 immunogen is recombinant protein fragment corresponding to a region within amino acids 83 and 257 of Human KATNA1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases.
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Protein Aliases: katanin p60 (ATPase containing) subunit A 1; katanin p60 (ATPase-containing) subunit A 1; Katanin p60 ATPase-containing subunit A1; Katanin p60 subunit A1; KATNA1; p60 katanin
Gene Aliases: KATNA1
UniProt ID: (Human) O75449
Entrez Gene ID: (Human) 11104