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Invitrogen
KBTBD3 Polyclonal Antibody
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FIGURE: 1 / 1
KBTBD3 Antibody (PA5-96074) in WB
Western blot analysis of KBTBD3 in extracts of PC-3 cells. Samples were incubated with KBTBD3 Polyclonal antibody (Product # PA5-96074) followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Product Details
PA5-96074
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 410-607 of mouse KBTBD3 (NP_0812382)
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Amount
48 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GSQDIKSLLD VESYNPLSRE WTSVSPLPRG IYYPEASACQ NIIYVLGSEV EIADAFNPSL DCFFKYNATT DQWSELVAEF GQFFHATLIK AVPVNCTLYI CDLSTYKVYS FCPDTCVWKG EGSFECAGFN AGAIGIEDKI YILGGDYAPD EITDEVQVYH SSRSEWEEVS PMPRALTEFY CQVIQFNKYR DPWYSNHF; Positive Samples: PC-3
Target Information
The BTB (Broad-Complex, Tram track and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KBTBD3 (kelch repeat and BTB domain-containing protein 3), also known as BKLHD3, is a 608 amino acid protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain and five kelch repeats. The gene encoding KBTBD3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BTB and kelch domain containing 3; BTB and kelch domain-containing protein 3; epididymis secretory sperm binding protein; kelch repeat and BTB (POZ) domain containing 3; Kelch repeat and BTB domain-containing protein 3; unnamed protein product
Gene Aliases: BKLHD3; KBTBD3
UniProt ID: (Human) Q8NAB2
Entrez Gene ID: (Human) 143879
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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