Immunogen sequence: METTNGTETW YESLHAVLKA LNATLHSNLL CRPGPGLGPD NQTEERRASL PGRDDN
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 80%.
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cardiac voltage-gated potassium channel accessory subunit; HOKPP; HYPP; KCNE3; Minimum potassium ion channel-related peptide 2; MinK-related peptide 2; MiRP2; Potassium channel subunit beta MiRP2; potassium channel, voltage gated subfamily E regulatory beta subunit 3; Potassium voltage-gated channel subfamily E member 3; potassium voltage-gated channel, Isk-related family, member 3; voltage-gated K+ channel subunit MIRP2
Gene Aliases: HOKPP; HYPP; KCNE3; MiRP2
UniProt ID: (Human) Q9Y6H6
Entrez Gene ID: (Human) 10008