Peptide sequence: GKYRTISQIP QFTLNFVEFN LEKHRSSSTT EIEIIAPHKV VERTQNVTEK
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH6 encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit.
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Protein Aliases: Eag-related gene member 2; eag-related protein 2; ERG-2; ERG2; Ether-a-go-go-related gene potassium channel 2; ether-a-go-go-related protein 2; HERG2; Kv11.2; potassium channel, voltage gated eag related subfamily H, member 6; Potassium voltage-gated channel; Potassium voltage-gated channel subfamily H member 6; potassium voltage-gated channel, subfamily H (eag-related), member 6; potassium voltage-gated channel, subfamily H, member 6; subfamily H (eag-related) member 6; Voltage-gated potassium channel subunit Kv11.2
Gene Aliases: BOS_19320; ERG-2; ERG2; hERG-2; HERG2; KCNH6; Kv11.2; m-erg2