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Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
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Protein Aliases: Inward rectifier K(+) channel Kir2.6; Inward rectifier potassium channel 18; inwardly rectifying potassium channel 18; Potassium channel, inwardly rectifying subfamily J member 18; potassium channel, inwardly rectifying subfamily J, member 18; thyrotoxic periodic paralysis susceptibility ion channel
Gene Aliases: KCNJ18; KIR2.6; TTPP2
UniProt ID: (Human) B7U540
Entrez Gene ID: (Human) 100134444
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