Proteintech

KCTD2/5/17 Polyclonal Antibody

7 References

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (7)

KCTD2/5/17 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 7

KCTD2/5/17 Antibody (15553-1-AP) in ICC/IF

Immunofluorescent analysis of Hela cells, using KCTD5 antibody 15553-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

KCTD2/5/17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

KCTD2/5/17 Antibody in Western Blot (WB)

KCTD2/5/17 Antibody in Flow Cytometry (Flow)

KCTD2/5/17 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

15553-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KCTD2/5/17 Fusion Protein Ag7915 (1-234 aa encoded by BC007314)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This polyclonal antibody raised against full-length recombinant protein of human KCTD5 (26 kDa) can cross-react with other KCTD proteins, including KCTD2 (29 kDa), KCTD17 (33-36 kDa).

Immunogen sequence: MAENHCELL SPARGGIGAG LGGGLCRRCS AGLGALAQRP GSVSKWVRLN VGGTYFLTTR QTLCRDPKSF LYRLCQADPD LDSDKDETGA YLIDRDPTYF GPVLNYLRHG KLVINKDLAE EGVLEEAEFY NITSLIKLVK DKIRERDSKT SQVPVKHVYR VLQCQEEELT QMVSTMSDGW KFEQLVSIGS SYNYGNEDQA EFLCVVSKEL HNTPYGTASE PSEKAKILQE RGSRM (1-234 aa encoded by BC007314)

Target Information

KCTD5 belongs to the human potassium (K+) channel tetramerization domain (KCTD) family of proteins which share sequence similarity with the cytoplasmic domain of voltage-gated K+channels (Kv channels). The KCTD proteins have relatively conserved N-terminal domains and variable C-termini. KCTD5 interacts with cullin3 and has been proposed to function as substrate adapter for cullin3 based ubiquitin E3 ligases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.

Cell reports

Ding P,Xu Y,Li L,Lv X,Li L,Chen J,Zhou D,Wang X,Wang Q,Zhang W,Liao T,Ji QH,Lei QY,Hu W

Tue May 31 00:00:00 UTC 2022

Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer.

Nature communications

Gogleva A,Polychronopoulos D,Pfeifer M,Poroshin V,Ughetto M,Martin MJ,Thorpe H,Bornot A,Smith PD,Sidders B,Dry JR,Ahdesmäki M,McDermott U,Papa E,Bulusu KC

Tue Mar 29 00:00:00 UTC 2022

HOXC10 Suppresses Browning to Maintain White Adipocyte Identity.

Diabetes

Tan HYA,Sim MFM,Tan SX,Ng Y,Gan SY,Li H,Neo SP,Gunaratne J,Xu F,Han W

Sun Aug 01 00:00:00 UTC 2021

Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.

Journal of proteome research

Young BD,Sha J,Vashisht AA,Wohlschlegel JA

Fri Sep 03 00:00:00 UTC 2021

Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.

Journal of proteome research

Young BD,Sha J,Vashisht AA,Wohlschlegel JA

Fri Sep 03 00:00:00 UTC 2021

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.

eLife

Zeng H,Castillo-Cabrera J,Manser M,Lu B,Yang Z,Strande V,Begue D,Zamponi R,Qiu S,Sigoillot F,Wang Q,Lindeman A,Reece-Hoyes JS,Russ C,Bonenfant D,Jiang X,Wang Y,Cong F

Tue Nov 19 00:00:00 UTC 2019

Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function.

PLoS genetics

Li Q,Kellner DA,Hatch HAM,Yumita T,Sanchez S,Machold RP,Frank CA,Stavropoulos N

Mon May 01 00:00:00 UTC 2017

Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function.

PLoS genetics

Li Q,Kellner DA,Hatch HAM,Yumita T,Sanchez S,Machold RP,Frank CA,Stavropoulos N

Mon May 01 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: BTB/POZ domain-containing protein KCTD17; BTB/POZ domain-containing protein KCTD2; BTB/POZ domain-containing protein KCTD5; potassium channel tetramerisation domain containing 17; potassium channel tetramerisation domain containing 2; potassium channel tetramerisation domain containing 5; potassium channel tetramerization domain containing 2; Potassium channel tetramerization domain-containing protein 2

View more View less

Gene Aliases: 2310012I15Rik; 2610030N08Rik; 2900008M13Rik; AA414907; AW742389; KCTD17; KCTD2; KCTD5; KIAA0176; mKIAA0176; N28155; RGD1311154; RGD1566063

View more View less

UniProt ID: (Human) Q8N5Z5, (Human) Q14681, (Human) Q9NXV2, (Mouse) Q8VC57, (Rat) B5DEL1

View more View less

Entrez Gene ID: (Human) 79734, (Human) 23510, (Human) 54442, (Mouse) 72844, (Rat) 300317, (Mouse) 70382, (Rat) 498024, (Mouse) 69259, (Rat) 287109

View more View less

Function(s)

protein binding identical protein binding cullin family protein binding protein complex binding

Process(es)

viral process protein homooligomerization biological_process cell projection organization endoplasmic reticulum calcium ion homeostasis proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of cilium assembly

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

KCTD2/5/17 Polyclonal Antibody

KCTD2/5/17 Antibody (15553-1-AP) in ICC/IF

Product Details

15553-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!