Keep as concentrated solution.
Positive Control: 293T, A431, Raji, mouse brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain however, these channels prevent reverse-propagation of action potentials. Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins). KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate its function. There are currently three known KChIPs; KChIP1 expressed in the brain; KChIP2 expressed in the brain, heart, and lung, and has three isoforms, a, b, and c; and KChIP3, also known as calsenilin and DREAM (downstream regulatory elements (DRE)-antagonist modulator) which is expressed in the brain and testis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A-type potassium channel modulatory protein 2; A-type potassium channel modulatory protein 2 antibody; Cardiac voltage-gated potassium channel modulatory subunit; cardiac voltage-gated potassium channel modulatory subunit antibody; DKFZp566L1246 antibody; KChIP2; KCHIP2 antibody; KCNIP2 antibody; Kv channel interacting protein 2; Kv channel interacting protein 2 antibody; Kv channel-interacting protein 2; Kv channel-interacting protein 2 antibody; MGC17241 antibody; Potassium channel-interacting protein 2; potassium channel-interacting protein 2 antibody
Gene Aliases: KCHIP2; KCNIP2