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Product Details
18055-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KIRREL3 Fusion Protein Ag12573 (28-381 aa encoded by BC101801)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: CLVLGYMAK DKFRRMNEGQ VYSFSQQPQD QVVVSGQPVT LLCAIPEYDG FVLWIKDGLA LGVGRDLSSY PQYLVVGNHL SGEHHLKILR AELQDDAVYE CQAIQAAIRS RPARLTVLVP PDDPVILGGP VISLRAGDPL NLTCHADNAK PAASIIWLRK GEVINGATYS KTLLRDGKRE SIVSTLFISP GDVENGQSIV CRATNKAIPG GKETSVTIDI QHPPLVNLSV EPQPVLEDNV VTFHCSAKAN PAVTQYRWAK RGQIIKEASG EVYRTTVDYT YFSEPVSCEV TNALGSTNLS RTVDVYFGPR MTTEPQSLLV DLGSDAIFSC AWTGNPSLTI VWMKRGSGVV LSNEK (28-381 aa encoded by B C101801)
Target Information
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Kin of IRRE-like protein 3; Kin of irregular chiasm-like protein 3; membrane protein mKirre; mKirre; nephrin-like 2; Nephrin-like protein 2; X kin of IRRE like 3
Gene Aliases: 1500010O20Rik; 2900036G11Rik; KIAA1867; KIRRE; KIRREL3; mKIAA1867; MRD4; NEPH2; PRO4502; SST4; UNQ5923/PRO4502/PRO19814
UniProt ID: (Human) Q8IZU9, (Mouse) Q8BR86
Entrez Gene ID: (Human) 84623, (Mouse) 67703, (Rat) 315546
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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