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A suggested positive control is 293 cell lysate.
PA5-20674 can be used with blocking peptide PEP-0792.
Ly49A is a gene that encodes a protein expressed on the surface of natural killer cells, which is involved in recognizing and eliminating virally infected or cancerous cells. It is located on chromosome 6 and is part of a larger family of genes that encode for similar receptors. The Ly49A protein interacts with a variety of ligands, including certain viruses and tumor cells, and is involved in regulating the activation and function of natural killer cells. Mutations or variations in the Ly49A gene have been associated with various diseases and conditions, including autoimmune disorders and cancer.
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Protein Aliases: class I MHC receptor KLRA22; killer cell lectin-like receptor 2; killer cell lectin-like receptor, subfamily A, member 2; KLRA#; ly-49a; Ly49 inhibitory receptor 8; lymphocyte antigen 49a; natural killer cell receptor Ly49A; novel killer cell lectin-like receptor subfamily A protein; t lymphocyte antigen A1; T-cell surface glycoprotein YE1/48
Gene Aliases: A1; CH29-493D4.3; KLRA1; Klra2; Klra22; KLRAP1; Ly-49L; Ly49; Ly49a; Ly49i8; LY49L; Ly49o<129>; Ly49v
Entrez Gene ID: (Human) 10748, (Mouse) 16627, (Rat) 494194
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