Invitrogen

KMO Polyclonal Antibody

Product Image Gallery

KMO Antibody in Western Blot (WB) — Western blot analysis of KMO in mouse brain (Lane 1: treated with blocking peptide). Samples were incubated with KMO polyclonal antibody (Product # PA5-100019).

KMO Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of paraffin-embedded KMO in mouse liver tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with KMO polyclonal antibody (Product # PA5-100019) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2000

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human KMO, corresponding to a region within the internal amino acids.

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol, 150mM NaCl

Contains

0.02% sodium azide

Storage conditions

-20°C

RRID

AB_2815549

Target Information

Kynurenine 3-monooxygenase (KMO; EC 1.14.13.9) is an NADPH-dependent flavin monooxygenase that catalyzes the hydroxylation of the L-tryptophan metabolite L-kynurenine to form L-3-hydroxykynurenine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: KMO; kmo {ECO:0000312|RGD:620610}; Kynurenine 3-hydroxylase; kynurenine 3-hydroxylase {ECO:0000255|HAMAP-Rule:MF_03018}; Kynurenine 3-monooxygenase; kynurenine 3-monooxygenase {ECO:0000255|HAMAP-Rule:MF_03018}

Gene Aliases: AI046660; dJ317G22.1; KMO

UniProt ID: (Human) O15229, (Mouse) Q91WN4, (Rat) O88867

Entrez Gene ID: (Human) 8564, (Mouse) 98256, (Rat) 59113

Molecular Function: oxidoreductase oxygenase