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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • KPNA4 Antibodies

          Bethyl Laboratories

          KPNA4 Polyclonal Antibody

          View all (11) KPNA4 antibodies

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          Cite KPNA4 Polyclonal Antibody

          • Antibody Testing Data (2)
          KPNA4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          KPNA4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          KPNA4 Antibody (A301-627A) in IHC (P)

          Detection of human KPNA4 by immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-KPNA4 (Product # A301-627A) (Lot 1) used at a dilution of 1:200 (1 µg/mL). Detection: DAB. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          KPNA4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          KPNA4 Antibody in Western Blot (WB)
          KPNA4 Polyclonal Antibody

          Product Details

          A301-627A

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:10,000
          -

          Immunohistochemistry (IHC)

          1:100-1:500
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:500
          -

          Immunoprecipitation (IP)

          2-5 µg/mg lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 471 and 521 of human karyopherin alpha 4.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.20 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          TBS, pH 7.0 to 8.0, with 0.1% BSA

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

          Target Information

          The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Importin alpha Q1; Importin subunit alpha-3; importin subunit alpha-4; importin-alpha-Q1; karyopherin alpha 4; karyopherin alpha 4 (importin alpha 3); Karyopherin subunit alpha-4; MGC12217; MGC26703; Qip1; Qip1 protein

          View more View less

          Gene Aliases: IPOA3; KPNA4; QIP1; SRP3

          View more View less

          UniProt ID: (Human) O00629

          View more View less

          Entrez Gene ID: (Human) 3840

          View more View less

          Function(s)
          protein binding nuclear localization sequence binding protein transporter activity transporter
          Process(es)
          NLS-bearing protein import into nucleus modulation by virus of host process response to hydrogen peroxide intracellular transport of virus
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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