This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: LFLTPDCKSL WNGDTGECTD NAYIDIQLRI ASFSQNCDIY PGKDFVQPPT KICVGCPRDI PTNSPELEET LTHTITKLNA ENNATFYFKI DNVKKARVQV VAGKKYFIDF VARETTCSKE SNEELTESCE TK
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
Protein Aliases: Alpha-2-thiol proteinase inhibitor; Bradykinin; Fitzgerald factor; High molecular weight kininogen; HMWK; Ile-Ser-Bradykinin; Kallidin I; Kallidin II; Kininogen-1; Kininogen-1 heavy chain; Kininogen-1 light chain; Low molecular weight growth-promoting factor; Lysyl-bradykinin; T-kinin; Williams-Fitzgerald-Flaujeac factor
Gene Aliases: BDK; BK; KNG; KNG1
UniProt ID: (Human) P01042
Entrez Gene ID: (Human) 3827
Molecular Function: protease inhibitor