|ChIP assay (ChIP)||Assay-dependent|
|Western Blot (WB)||1:500-1:3000|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 406 and 705 of Human L3MBTL2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28549 targets L3MBTL2 in WB applications and shows reactivity with Human samples.
The PA5-28549 immunogen is recombinant fragment corresponding to a region within amino acids 406 and 705 of Human L3MBTL2.
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H-l(3)mbt-l; H-l(3)mbt-like protein 2; l(3)mbt-like 2; L(3)mbt-like protein 2; L3MBT; Lethal(3)malignant brain tumor-like protein 2; lmbt-like 2 (Drosophila) isoform 1; lmbt-like 2 (Drosophila) isoform 2
Gene Aliases: H-l(3)mbt-l; L3MBT; L3MBTL2
UniProt ID: (Human) Q969R5
Entrez Gene ID: (Human) 83746
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