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Invitrogen
LAPTM4B Polyclonal Antibody
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FIGURE: 1 / 4
LAPTM4B Antibody (PA5-117686) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of LAPTM4B in SH-SY5Y cells using LAPTM4B Polyclonal Antibody (Product # PA5-117686) diluted at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Product Details
PA5-117686
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Lysosomal-associated transmembrane protein 4B protein (174-226aa)
Conjugate
Form
Liquid
Concentration
4.82 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody has been tested in direct-ELISA
Target Information
LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: lysosomal associated protein transmembrane 4 beta; Lysosomal-associated transmembrane protein 4B; Lysosome-associated transmembrane protein 4-beta
Gene Aliases: LAPTM4B; LAPTM4beta; LC27; PSEC0001
UniProt ID: (Human) Q86VI4
Entrez Gene ID: (Human) 55353
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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