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Invitrogen
LARS Polyclonal Antibody
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Product Details
PA5150150
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Leucyl tRNA Synthetase (LARS) (Gly260-Leu478)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. Alternatively spliced transcript variants of this gene have been found; however, their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytoplasmic leucyl-tRNA synthetase; cytosolic leucyl-tRNA synthetase; leucine translase; leucine tRNA ligase 1, cytoplasmic; Leucine--tRNA ligase, cytoplasmic; leucine-tRNA ligase; Leucyl-tRNA synthetase; leucyl-tRNA synthetase, cytoplasmic; LeuRS; PIG57; proliferation-inducing gene 44; unnamed protein product
Gene Aliases: 2310045K21Rik; 3110009L02Rik; AW536573; cLRS; hr025Cl; HSPC192; ILFS1; KIAA1352; LARS; LARS1; LEURS; LEUS; LFIS; LRS; mKIAA1352; PIG44; RNTLS
UniProt ID: (Human) Q9P2J5, (Mouse) Q8BMJ2
Entrez Gene ID: (Human) 51520, (Mouse) 107045, (Rat) 291624
translation
tRNA aminoacylation for protein translation
glutaminyl-tRNA aminoacylation
leucyl-tRNA aminoacylation
regulation of cell size
positive regulation of TOR signaling
cellular response to amino acid starvation
positive regulation of GTPase activity
cellular response to amino acid stimulus
cellular response to leucine
aminoacyl-tRNA metabolism involved in translational fidelity
positive regulation of TORC1 signaling
cellular response to leucine starvation
methionyl-tRNA aminoacylation
regulation of translational fidelity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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