Immunogen sequence: PHFIAKRVTYD SDATSSACRE
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DnaJ (Hsp40) homolog, subfamily C, member 6; Endospanin-1; LEPR; leptin receptor gene related protein; Leptin receptor gene-related protein; Leptin receptor overlapping transcript protein; OB-R gene-related protein; OB-RGRP; OBR
Gene Aliases: LEPR; LEPROT; OB-RGRP; OBR; OBRGRP; VPS55
UniProt ID: (Human) O15243
Entrez Gene ID: (Human) 54741