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Invitrogen
LHX3 Polyclonal Antibody
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FIGURE: 1 / 5
LHX3 Antibody (PA5-117410) in ICC/IF
Immunocytochemistry analysis of LHX3 in 4% paraformaldehyde (RT, 15 min) fixed DIV10 rat E18 primary cortical neuron cells (Green: LHX3, Red: Tau). Samples was incubated in LHX3 polyclonal antibody (Product # PA5-117410) using a dilution of 1:500, followed by DAPI.
Product Details
PA5-117410
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of mouse LHX3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.86 mg/mL
Amount
86 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Centrifuge briefly prior to opening.
Target Information
This gene encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp762A2013; Homeobox protein LIM-3; Homeobox protein P-LIM; LIM homeo box protein 3; LIM homeobox protein 3; LIM/homeobox protein Lhx3
Gene Aliases: Lhx3; Lim-3; Lim3; mLim-3; mLIM3; P-LIM; Plim
UniProt ID: (Mouse) P50481
Entrez Gene ID: (Rat) 170671, (Mouse) 16871
transcription factor activity, RNA polymerase II transcription factor binding
molecular_function
zinc ion binding
sequence-specific DNA binding
DNA binding
protein binding
metal ion binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
placenta development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
motor neuron axon guidance
dorsal/ventral pattern formation
spinal cord motor neuron cell fate specification
ventral spinal cord interneuron specification
medial motor column neuron differentiation
spinal cord association neuron differentiation
pituitary gland development
cell differentiation
lung development
negative regulation of apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
inner ear development
transcription, DNA-templated
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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