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Proteintech
LHX5 Polyclonal Antibody
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Product Details
21567-1-AP
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LHX5 Fusion Protein Ag16081 (260-402 aa encoded by BC109230)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PLGGRLDES EMLGSTPYTY YGDYQGDYYA PGSNYDFFAH GPPSQAQSPA DSSFLAASGP GSTPLGALEP PLAGPHAADN PRFTDMISHP DTPSPEPGLP GTLHPMPGEV FSGGPSPPFP MSGTSGYSGP LSHPNPELNE AAVW (260-402 aa encoded by B C109230)
Target Information
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LIM homeo box protein 5; LIM homeobox protein 5; LIM/homeobox protein Lhx5; MGC129689
Gene Aliases: LHX5; Lim2
UniProt ID: (Human) Q9H2C1, (Mouse) P61375
Entrez Gene ID: (Human) 64211, (Mouse) 16873
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
metal ion binding
sequence-specific double-stranded DNA binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell-cell signaling
neuroblast proliferation
spinal cord association neuron differentiation
cerebellum development
cerebellar Purkinje cell differentiation
hippocampus development
cell proliferation in forebrain
forebrain neuron differentiation
cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
neuron differentiation
positive regulation of transcription, DNA-templated
regulation of neuroblast proliferation
transcription, DNA-templated
regulation of cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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