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Fabgennix
LILRB3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
LILRB3-301AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 800-841 on mouse LILRB3 protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell-surface glycoprotein p91; extracellular domain; immunoglobulin-like receptor; leukocyte immunoglobulin-like receptor 3; leukocyte immunoglobulin-like receptor subfamily B member 3; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; unnamed protein product
Gene Aliases: Gp91; Lilrb3; LIR-3; PIR-B
UniProt ID: (Mouse) P97484
Entrez Gene ID: (Mouse) 18733
beta-amyloid binding
IgM binding
receptor binding
protein binding
protein phosphatase 1 binding
coreceptor activity
MHC class Ib protein complex binding
MHC class Ib protein binding
HLA-A specific inhibitory MHC class I receptor activity
HLA-B specific inhibitory MHC class I receptor activity
MHC class I receptor activity
MHC class Ib receptor activity
inhibitory MHC class I receptor activity
SH2 domain binding
MHC class I protein binding
protein homodimerization activity
macromolecular complex binding
cell adhesion molecule binding
B cell homeostasis
immune response-inhibiting cell surface receptor signaling pathway
cell surface receptor signaling pathway
learning or memory
cytokine-mediated signaling pathway
B cell mediated immunity
myeloid dendritic cell differentiation
negative regulation of protein metabolic process
regulation of long-term synaptic potentiation
positive regulation of long term synaptic depression
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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