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Proteintech
LIMCH1 Polyclonal Antibody
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Product Details
26561-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LIMCH1 fusion protein Ag24112
Conjugate
Form
Liquid
Concentration
0.75 mg/mL
Amount
112.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: RWKSRRRSVS QDLIKKEEER KKMEKLLAGE DGTSERRKSI KTYREIVQEK ERRERELHEA YKNARSQEEA EGILQQYIER FTISEAVLER LEMPKILERS HSTEPNLSSF LNDPNPMKYL RQQSLPPPKF TATVETTIAR ASVLDTSMSA GSGSPSKTVT PKAVPMLTPK PYSQPKNSQD VLKTFKVDGK VSVNGETVHR EEEKERECPT VAPAHSLTKS QMFEGVARVH GSPLELKQDN GSIEINIKKP NSVPQELAAT TEKTEPNSQE DKNDGGKSRK GNIELASSEP QHFTTTVTRC SPTVAFVEFP SSPQLKNDVS EEKDQKKPEN EMSGKVELVL SQKVVKPKSP EPEATL
Target Information
Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LIM and calponin homology domains-containing protein 1; unnamed protein product
Gene Aliases: KIAA1102; LIMCH1; LIMCH1A; LMO7B
UniProt ID: (Human) Q9UPQ0
Entrez Gene ID: (Human) 22998
positive regulation of protein phosphorylation
positive regulation of macromolecule metabolic process
negative regulation of cell migration
actomyosin structure organization
positive regulation of stress fiber assembly
regulation of focal adhesion assembly
cytoplasmic actin-based contraction involved in cell motility
regulation of primary metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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