Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ILK-binding protein; LIM and senescent cell antigen-like domains 2; LIM and senescent cell antigen-like-containing domain protein 2; LIM-like protein 2; LIM-type zinc finger domains 2; Particularly interesting new Cys-His protein 2; PINCH-2
Gene Aliases: LGMD2W; LIMS2; PINCH-2; PINCH2
Molecular Function: cell junction protein