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Invitrogen
LIPA Polyclonal Antibody
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FIGURE: 1 / 1
LIPA Antibody (PA5-109918) in WB
Western blot analysis of LIPA in extracts of various cell lines. Samples were incubated with LIPA Polyclonal antibody (Product # PA5-109918) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-109918
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 110-399 of human LIPA (NP_001121077.1).
Conjugate
Form
Liquid
Concentration
2.17 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DAGFDVWMGN SRGNTWSRKH KTLSVSQDEF WAFSYDEMAK YDLPASINFI LNKTGQEQVY YVGHSQGTTI GFIAFSQIPE LAKRIKMFFA LGPVASVAFC TSPMAKLGRL PDHLIKDLFG DKEFLPQSAF LKWLGTHVCT HVILKELCGN LCFLLCGFNE RNLNMSRVDV YTTHSPAGTS VQNMLHWSQA VKFQKFQAFD WGSSAKNYFH YNQSYPPTYN VKDMLVPTAV WSGGHDWLAD VYDVNILLTQ ITNLVFHESI PEWEHLDFIW GLDAPWRLYN KIINLMRKYQ
Target Information
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acid cholesteryl ester hydrolase; cholesterol ester hydrolase; Cholesterol esterase (pancreatic) see D3Wox12 D3Wox13 D3Wox26 and D3Mgh25; Cholesteryl esterase; Diacylglycerol lipase; Lipase A; lipase A, lysosomal acid, cholesterol esterase; lysosomal acid lipase; lysosomal acid lipase 1; lysosomal acid lipase A; Lysosomal acid lipase/cholesteryl ester hydrolase; pancreatic cholesterol esterase; RP11-341B24.1; Sterol esterase; Triacylglycerol ester hydrolase; Triacylglycerol lipase
Gene Aliases: CESD; Chole; Chole2; LAL; Lip1; LIPA
UniProt ID: (Human) P38571
Entrez Gene ID: (Human) 3988, (Rat) 25055
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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