In IHC applications, antigen retrieval using Proteinase K treatment is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Panda, Dog, Bat, Elephant (94%) Mouse, Rat, Horse, Hamster (88%) Pig, Bovine (81%).
EDG7 is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.EDG7 has been reported in human prostate, as well as rodent brain, kidney, lung, placenta, prostate, and testis. ESTs have been isolated from a normal prostate library, as well as cancer libraries of the head/neck, ovary, and thyroid.
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Protein Aliases: 7; calcium-mobilizing lysophosphatidic acid receptor LP-A3; Edg-7; EDG7; endothelial cell differentiation gene 7; endothelial differentiation; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7; GPCR; HOFNH30; LP-A3; LPA receptor 3; LPA receptor EDG7; LPA-3; LPA3; lysophosphatidic acid G-protein-coupled receptor; Lysophosphatidic acid receptor 3; Lysophosphatidic acid receptor Edg-7; RP4-678I3
Gene Aliases: Edg-7; EDG7; GPCR; HOFNH30; LP-A3; LPA3; LPAR3; RP4-678I3
UniProt ID: (Human) Q9UBY5
Entrez Gene ID: (Human) 23566