Recommended positive controls: A431, H1299, HeLa, Molt-4.
Predicted reactivity: Human (99%), Mouse (96%), Rat (95%), Cat (97%), Pig (96%), Rabbit (96%), Chicken (80%), Sheep (96%), Bovine (96%), Guinea pig (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha lipase; Lipoprotein lipase; LPL; O 1-4-5; Phospholipase A1
Gene Aliases: HDLCQ11; LIPD; LPL
Molecular Function: lipase