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Invitrogen
LPL Polyclonal Antibody
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LPL Antibody (PA5-34812) in WB
Western blot analysis of LPL was performed by separating 50 µg of mouse tissue extract by 10% SDS-PAGE. Proteins were transferred to a membrane and probed with a LPL Polyclonal Antibody (Product # PA5-34812) at a dilution of 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Product Details
PA5-34812
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human LPL. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.35 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: A431, H1299, HeLa, Molt-4.
Predicted reactivity: Human (99%), Mouse (96%), Rat (95%), Cat (97%), Pig (96%), Rabbit (96%), Chicken (80%), Sheep (96%), Bovine (96%), Guinea pig (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha lipase; Lipoprotein lipase; LPL; O 1-4-5; Phospholipase A1
Gene Aliases: Lpl
UniProt ID: (Mouse) P11152
Entrez Gene ID: (Mouse) 16956
lipid metabolic process
fatty acid biosynthetic process
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol storage
positive regulation of sequestering of triglyceride
lipid catabolic process
triglyceride biosynthetic process
triglyceride catabolic process
very-low-density lipoprotein particle remodeling
triglyceride homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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