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Invitrogen
LPL Polyclonal Antibody
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LPL Antibody (PA5-71881) in IHC (P)
Immunohistochemistry analysis of LPL in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with LPL polyclonal antibody (Product # PA5-71881) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-71881
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
C. elegans
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 300-327 amino acids from the Central region of human LPL
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alpha lipase; Lipoprotein lipase; LPL; Phospholipase A1
Gene Aliases: HDLCQ11; LIPD; LPL
UniProt ID: (Human) P06858
Entrez Gene ID: (Human) 4023
retinoid metabolic process
fatty acid biosynthetic process
triglyceride metabolic process
phospholipid metabolic process
response to cold
response to glucose
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol storage
positive regulation of sequestering of triglyceride
triglyceride biosynthetic process
triglyceride catabolic process
chylomicron remodeling
very-low-density lipoprotein particle remodeling
lipoprotein metabolic process
response to drug
cholesterol homeostasis
positive regulation of inflammatory response
triglyceride homeostasis
positive regulation of chemokine secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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