Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
LRP1, also known as Low density lipoprotein receptor-related protein 1 or CD91, is a protein forming a receptor found in the plasma membrane of cells involved in receptor-mediated endocytosis. It is mapped to 12q13.3. In humans, the LRP1 protein is encoded by the LRP1 gene. It is mapped to 12q13.3. LRP1 is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. LRP1 showed strong calcium binding. It mediates the endocytosis and degradation of secreted amyloid precursor protein, suggesting that a single metabolic pathway links 2 molecules implicated in the pathophysiology of Alzheimer disease, LRP1 has a role in macrophage migration and that it is critical for internalization of integrin alpha-M/beta-2.
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Protein Aliases: A2MR; Alpha-2-macroglobulin receptor; APOER; Apolipoprotein E receptor; CD91; low density lipoprotein receptor-related protein 1; Low-density lipoprotein receptor-related protein 1 515 kDa subunit; Low-density lipoprotein receptor-related protein 1 85 kDa subunit; Low-density lipoprotein receptor-related protein 1 intracellular domain; LRP-1; LRP-515; LRP-85; LRPICD; Prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; type V tgf-beta receptor
Gene Aliases: A2MR; APOER; APR; CD91; IGFBP3R; LRP; LRP1; LRP1A; TGFBR5
UniProt ID: (Human) Q07954
Entrez Gene ID: (Human) 4035