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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 213 and 575 of Human LRRN2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27923 targets LRRN2 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27923 immunogen is recombinant fragment corresponding to a region within amino acids 213 and 575 of Human LRRN2.
The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
fibronectin type III; fibronectin type III, immunoglobulin and leucine rich repeat domain 7; FIGLER7; GAC1; Glioma amplified on chromosome 1 protein; immunoglobulin and leucine rich repeat domain 7; leucine rich and ankyrin repeats 1; leucine rich repeat neuronal 5; Leucine-rich repeat neuronal protein 2; Leucine-rich repeat neuronal protein 5; LRANK1; LRRN5
FIGLER7; GAC1; LRANK1; LRRN2; LRRN5; UNQ256/PRO293