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          • Primary Antibodies ›
          • LSS Antibodies

          Huabio

          LSS Polyclonal Antibody

          View all (8) LSS antibodies

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          Cite LSS Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (5)
          LSS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          LSS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          LSS Antibody (HA500011) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using anti-LSS antibody. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (HA500011, 1:400) for 30 minutes at room temperat... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          LSS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          LSS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          LSS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          LSS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          LSS Antibody in Western Blot (WB)
          LSS Polyclonal Antibody

          Product Details

          HA500011

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein within human LSS aa 1-200.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          TBS, pH 7.4, with 0.2% BSA, 50% glycerol

          Contains

          0.05% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          The protein encoded by this gene catalyzes the conversion of (S)-2, 3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 2,3-epoxysqualene--lanosterol cyclase; 2,3-epoxysqualene-lanosterol cyclase; epididymis secretory sperm binding protein; hOSC; Lanosterol synthase; lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase); OSC; Oxidosqualene--lanosterol cyclase; unnamed protein product

          View more View less

          Gene Aliases: 2810025N20Rik; APMR4; CTRCT44; D10Ertd116e; HYPT14; LSS; OSC

          View more View less

          UniProt ID: (Human) P48449, (Mouse) Q8BLN5

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          Entrez Gene ID: (Human) 4047, (Mouse) 16987

          View more View less

          Function(s)
          lanosterol synthase activity protein binding isomerase activity intramolecular transferase activity cyclase
          Process(es)
          lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process triterpenoid biosynthetic process regulation of protein stability
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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