Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.04-0.4 µg/mL | - |
Immunohistochemistry (IHC) |
1:50-1:200 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human LYPLA3 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.2 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2643631 |
Immunogen sequence: GVAKTLRVLA SGDNNRIPVI GPLKIREQQR SAVSTSWLLP YNYTWSPEKV FVQTPTINYT LRDYRKFFQD IGFED
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1-O-acylceramide synthase; 1-O-acylceramide synthase {ECO:0000303|PubMed:15294901}; ACS; ACS {ECO:0000303|PubMed:15294901}; group XV phospholipase A2; group XV phospholipase A2 {ECO:0000312|EMBL:AAH98894.1}; LCAT-like lysophospholipase; LCAT-like lysophospholipase {ECO:0000250|UniProtKB:Q8VEB4}; LLPL; LLPL {ECO:0000250|UniProtKB:Q8VEB4}; LPLA2; LPLA2 {ECO:0000303|PubMed:15294901}; Lysophospholipase 3; lysophospholipase 3 (lysosomal phospholipase A2); lysophospholipase 3 {ECO:0000250|UniProtKB:Q8VEB4}; Lysosomal phospholipase A and acyltransferase; Lysosomal phospholipase A2; lysosomal phospholipase A2 {ECO:0000303|PubMed:15294901, ECO:0000312|EMBL:AAS66767.1}; Phospholipase A2 group XV; phospholipase A2, group XV; pla2g15 {ECO:0000312|Ensembl:ENSRNOP00000026996, ECO:0000312|RGD:1302982}
Gene Aliases: 1-O-acylceramidesynthase; ACS; C87498; GXVPLA2; LLPL; LPLA2; LYPLA3; PLA2G15; UNQ341/PRO540
UniProt ID: (Human) Q8NCC3, (Mouse) Q8VEB4, (Rat) Q675A5
Entrez Gene ID: (Human) 23659, (Mouse) 192654, (Rat) 361401
Molecular Function:
acyltransferase
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